Why Pain Management Matters

• ➤ Musculoskeletal pain
  
• ➤ Neuropathic pain
  
• ➤ Arthritis and fibromyalgia
  
• ➤ Post-operative pain
  
• ➤ Chronic pain syndromes like diabetic neuropathy

With a focus on restoring function and relieving suffering, Osteokare therapies support patients across all age groups.


Innovation That Leads the Market



At the heart of Osteokare’s success is its flagship brand:

Nortipan M

A market leader in the Nortriptyline + Pregabalin + Methylcobalamin segment, Nortipan M is the first triple combination in India to offer sustained release pregabalin alongside nortriptyline and methylcobalamin. It is a trusted option in the treatment of:



• ➤ Chronic neuropathic pain
  
• ➤ Diabetic neuropathy
  
• ➤ Peripheral nerve disorders

This unique formulation delivers superior symptom relief, sets a new therapeutic benchmark, and has earned Nortipan M the No. 1 position in its segment.


All Osteokare products are Patient-Centric, Science-Driven:




• ➤ Clinically aligned with modern treatment protocols
  
• ➤ Developed to maximize therapeutic benefit while minimizing adverse effects
  
• ➤ Manufactured in WHO-GMP certified facilities with stringent quality control
  
• ➤ Affordable and accessible, helping expand care across urban and rural India

Our Commitment


• ➤ Empowering healthcare professionals with evidence-based, research-driven therapies
  
• ➤ Offering customized solutions tailored to each patient’s needs.
  
• ➤ Continuing to improve outcomes in the fields of bone health, musculoskeletal disorders, and neuropathic pain



Analgesic & Anti-inflammatory

Acenac Tablet


Description
ACENAC Tablets contain Aceclofenac which is a preferential COX 2 inhibitor. Exhibits multiple mechanisms of action. It blocks the prostaglandin (PGE2) secretion and inhibits the release of Cytokines, as well as it stimulates the synthesis of cartilages matrix and blocks its degeneration. Besides this it increases hexosamine level, a gastro protective agent. That's why GI side effects are less associated with this NSAID.
Indications
Rheumatoid Arthritis
Osteoarthritis
Spondylitis
Composition
Each film coated tablet contains :
Aceclofenac - 100 mg
Dosage
100 mg BID
Side Effects
• Aceclofenac is well tolerated.
• GI side effects like dyspepsia, abdominal pain, diarrhoea, and nausea are very rare.
Precautions
• As for NSAIDs in general.
• Aceclofenac should be avoided in patients with moderate to severe renal impairment.
Presentation
Acenac is available as a strip of 10 tablets.
Acenac-SR


Description
Cyclooxygenase-2 inhibitors effectively relieve osteoarthritis symptoms when taken in the morning and better results are obtained in rheumatoid arthritis when it is taken in the evening. For achieving longer duration of action and better compliance, drug levels are required to be maintained above effective therapeutic concentration for 24 hours in a day. Sustained release system achieves slow release of drug, which maintains the drug levels in blood or target tissue over an extended period of time. So it provides better efficacy in once daily dose for providing symptomatic relief in Chronic painful conditions like Osteoarthritis, Rheumatoid Arthritis & Spondylitis.
Indications
Osteoarthritis
Rheumatoid Arthritis
Spondylitis.
Composition
Each film coated sustained release tablet contains:
Aceclofenac Sustained Release - 200 mg
Dosage administration
In Osteoarthritis: 1 tablet of Acenac SR in the morning.
In Rheumatoid Arthritis: 1 tablet of Acenac SR at the night.
Side Effects
• Minor like dyspepsia
• Nausea
• Heartburn
Precautions
• As for NSAIDs in general.
• Aceclofenac should be avoided in patients with moderate to severe renal impairment.
Presentation
Acenac SR is available as a strip of 10 tablets.
ACENAC-P


Description
Pain is a complex phenomena involving both peripheral and central mechanism. The combination of aceclofenac with paracetamol (Acenac-P) gives complete relief from pain and associated inflammation by counter acting both central and peripheral mechanisms. Aceclofenac can counteract peripheral inflammation by blocking COX-2 enzyme and paracetamol block the central effects of prostaglandin by blocking COX-3 enzyme in brain. This combination offers faster and longer duration of action with least incidence of GI side-effects. It works hard on pain, hardly on stomach.
Indications


Acute low back pain
Postoperative pain especially after orthopedic surgeries


Dental pain
Dysmenorrhoea


Sprains and Injuries
 


Composition
Each film coated tablet contains
 


Aceclofenac
100 mg


Paracetamol IP
325 mg


Dosage
One tablet twice daily


Side Effects
Aceclofenac is well tolerated.
 


GI side effects like dyspepsia, abdominal pain, diarrhoea, and nausea are very rare.
 


 
 


Precautions
As for NSAIDs in general
 


Aceclofenac should be avoided in patients with moderate to severe renal impairment.
 


 
 


Presentation
ACENAC-P is available as a strip of 10 tablets
Acenac SP tablet


Composition Each tablet of Acenac SP contains: Aceclofenac 100 mg Paracetamol 325 mg Serratiopeptidase 15 mg (30,000 Serratiopeptidase units as enteric coated granules) Indications In pain & swelling associated with: Tonsillitis & pharyngitis Dental extractions & dental infections Post operative swelling Sprains and strains Presentation ACENAC-SP is available as a strip of 10 tablets

Nortipan tablet


Composition Each tablet of Nortipan contains: Nortriptyline 10 mg Pregabalin 75 mg Indications Neuropathic pain Diabetic neuropathy Surgical neuralgia Radiculopathy Sciatica Low back pain Postherpetic neuralgia Presentation Nortipan is available as a strip of 10 tablets

Nortipan M tablet


Composition Each tablet of Nortipan contains: Nortriptyline 10 mg Pregabalin SR 75 mg Methylcobalamin 1500 mcg Indications Diabetic neuropathy Sciatica Low back pain Post-herpetic Neuralgia Post-surgical Neuralgia Presentation Nortipan M is available as a strip of 10 tablets

NIMSAID – P


Description
Nimesulide act peripherally by blocking COX-2 while paracetamol works centrally by blocking COX-3. Both the drugs are well tolerated. The combination of Nimesulide with Paracetamol provides the advantage that the onset of analgesic and antipyretic effect starts faster and the duration of effect is long lasting. Thus combination of the two drugs for rapid and long lasting analgesic and antipyretic action is well justified
Indications
Body aches with fever
Pain

Composition
Each uncoated tablet contains:

Nimesulide
100mg


Paracetamol
325 mg


Dosage
One tablet to be taken twice daily

Side Effects
Well tolerated
Contraindication
Hypersensitivity to any ingredients
Presentation
NIMSAID – P is available as a strip of 10 tablets
Conjoint

Description
Conjoint is a combination of natural compounds such as curcumin and piperine. Curcumin exhibits analgesic and anti-inflammatory action. Curcumin targets mechanisms involved in progression of pain and inflammation whereas piperine increases the bioavailability of curcumin. Curcumin also exhibits strong anti-oxidant action and anti-cancer activities.
Indications
• Joint pain and discomfort
• Oral submucous fibrosis
• Psoriasis
Composition
Each capsule contains
Curcumin (95%)
500 mg


Piperine (95%)
5 mg


Dosage
1 capsule once or twice a day
Presentation
Strip of 10 capsules
Conjoint 3D

Description
Conjoint 3D contains a combination of ingredients that act together for joint restoration in the management of osteoarthritis. Undenatured collagen type II reduces chondrocyte destruction and increases extracellular matrix of cartilage. Hyaluronic acid improves lubrication of joints and restores elasticity and viscosity of synovia fluid. Nano curcumin and Acetyl Keto Beta Boswellic acid (AKBA) inhibit inflammatory mediators and reduces inflammation and pain.
Indications
• Osteoarthritis
• Inflammatory arthritis
• Patients awaiting knee replacement surgery
Composition
Each softgel capsule contains
Undenatured Collagen Type II
40 mg


Hyaluronic Acid
40 mg


Curcuminoids (Nano)
250 mg


Piper Nigrum
5 mg


Boswellia Serrata Roxb
30 mg


Dosage
One softgel capsule once daily
Presentation
Strip of 10 softgel capsules
Ketotram

Description
Ketotram is a combination of Ketorolac and Tramadol which relieve pain. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) which inhibits prostaglandin synthesis that cause pain and inflammation. Tramadol is an opioid analgesic which works by blocking transmission of pain signals to the brain to lower pain perception.
Indications
• Short-term treatment of moderate to severe traumatic pain origin (back pain, fractures, dislocations, sprains, cancer)
• Postoperative pain after major abdominal surgery
• Dental pain, Molar Extraction
• In the treatment of neuropathic pain
Composition
Each tablet contains:
Ketorolac tromethamine
10 mg


Tramadol hydrochloride
25 mg


Dosage
1 sublingual tablet every 12 hours, not to exceed 7 days of treatment
Contraindications
• In patients with hypersensitivity to tramadol & ketorolac
• In patients with active peptic ulcer, recent gastrointestinal bleeding
• In poisoning with alcohol
• Sleeping pills and psychotropic drugs
• Patients with moderate or severe renal impairment should be administered under closed medical supervision
• Pregnancy and lactation
Side-effects
Drowsiness and blurred vision.
Precautions
Ketotram should be used with caution in patients with kidney and liver disease.
Presentation
Strip of 10 tablets