Home / Products / Vazokare
Vazokare
Vazokare - Advancing Cardiometabolic Health


Vazokare, a dedicated division of Medley Pharmaceuticals, is committed to addressing lifestyle-related health challenges, with a specialized focus on Cardiology and Diabetology. Our mission is to enhance patient well-being by providing high-quality, affordable healthcare solutions that are both innovative and accessible.


India's Cardiometabolic Landscape:

India faces a significant burden of cardiovascular and metabolic diseases:

  • ➤ Hypertension affects a substantial portion of the adult population, with many requiring combination therapies for effective management.
  • ➤ Diabetes Mellitus, particularly Type 2, is on the rise, necessitating comprehensive treatment approaches.

These conditions often coexist, underscoring the need for integrated therapeutic strategies.


Our Therapeutic Focus:


  • ➤ Hypertension: Including various classes such as ACE inhibitors, ARBs, beta-blockers, calcium channel blockers, and diuretics.
  • ➤ Dyslipidemia: Statins and combination therapies to manage cholesterol levels.
  • ➤ Type 2 Diabetes Mellitus: Oral hypoglycemic agents and insulin sensitizers.
  • ➤ Heart Failure: Medications aimed at improving cardiac function and patient quality of life.

    Our products are developed in alignment with national and international clinical guidelines to ensure optimal patient outcomes.

    Innovation and Quality Assurance:

    • ➤ Research-Driven Solutions: Continuous investment in R&D to bring forth effective therapies.
    • ➤ Quality Manufacturing: All products are manufactured in WHO-GMP certified facilities, ensuring safety and efficacy.
    • ➤ Patient-Centric Approaches: Designing medications that improve adherence and simplify treatment regimens.

      Join Us in Transforming Health:

      With a legacy of trust and a vision for a healthier future, Vazokare invites you to explore our range of cardiometabolic solutions designed to meet the evolving needs of patients and healthcare providers alike.


      Anti hypertensive

      PRIMODIL 2.5MG
      Description
      Primodil (Amlodipine) is the second generation, long-acting calcium channel blocker. It is more selective for vascular smooth muscle than for myocardial tissue. It acts by primarily inhibiting the entry of calcium ions into the vascular smooth muscle. As we know, contractile process of smooth muscle is dependent upon the entry of extra cellular calcium ions into these cells through Ca++ channels. It is more selective for arteries. Thus, Amlodipine is also termed as arterial vasodilator. Because of this mode of action Primodil is effective in the management of mild to moderate hypertension as well as in both stable angina and vasospastic angina angina.
      Indications
      Hypertension
      Composition
      Each tab contains:
       

      Amlodipine
      2.5 mg

      Dosage
      For hypertension and angina, Primodil is given in the dose of 5 mg once daily. After two weeks, dosage may be increased to a maximum of 10 mg once daily.
      Angina pectoris: The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtained.
      For elderly patients and patients with hepatic dysfunction, therapy should begin with 2.5 mg once daily.
      Side Effects
      Amlodipine is well tolerated. Rarely can it cause ankle edema, headache, dizziness, somnolence, etc.
      Presentation
      PRIMODIL 2.5 MG is available as a strip of 10 tablets
      PRIMODIL 5 MG
      Description
      Primodil (Amlodipine) is the second generation, long-acting calcium channel blocker. It is more selective for vascular smooth muscle than for myocardial tissue. It acts by primarily inhibiting the entry of calcium ions into the vascular smooth muscle. As we know, contractile process of smooth muscle is dependent upon the entry of extra cellular calcium ions into these cells through Ca++ channels. It is more selective for arteries. Thus, Amlodipine is also termed as arterial vasodilator. Because of this mode of action Primodil is effective in the management of mild to moderate hypertension as well as in both stable angina and vasospastic angina angina.
      Indications
      Hypertension
      Composition
      Each tab contains:
       

      Amlodipine
      5 mg

      Dosage
      For hypertension and angina, Primodil is given in the dose of 5 mg once daily. After two weeks, dosage may be increased to a maximum of 10 mg once daily.
      Angina pectoris: The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtained.
      For elderly patients and patients with hepatic dysfunction, therapy should begin with 2.5 mg once daily.
      Side Effects
      Amlodipine is well tolerated. Rarely can it cause ankle edema, headache, dizziness, somnolence, etc.
      Presentation
      PRIMODIL 5 MG is available as a strip of 10 tablets
      PRIMODIL 10 MG
      Description
      Primodil (Amlodipine) is the second generation, long-acting calcium channel blocker. It is more selective for vascular smooth muscle than for myocardial tissue. It acts by primarily inhibiting the entry of calcium ions into the vascular smooth muscle. As we know, contractile process of smooth muscle is dependent upon the entry of extra cellular calcium ions into these cells through Ca++ channels. It is more selective for arteries. Thus, Amlodipine is also termed as arterial vasodilator. Because of this mode of action Primodil is effective in the management of mild to moderate hypertension as well as in both stable angina and vasospastic angina angina.
      Indications
      Hypertension
      Composition
      Each tab contains:
       

      Amlodipine
      10 mg

      Dosage
      For hypertension and angina, Primodil is given in the dose of 5 mg once daily. After two weeks, dosage may be increased to a maximum of 10 mg once daily.
      Angina pectoris: The dosage may be gradually increased at weekly intervals until optimum clinical response has been obtained.
      For elderly patients and patients with hepatic dysfunction, therapy should begin with 2.5 mg once daily.
      Side Effects
      Amlodipine is well tolerated. Rarely can it cause ankle edema, headache, dizziness, somnolence, etc.
      Presentation
      PRIMODIL 10 MG is available as a strip of 10 tablets
      PRIMODIL - L
      Description
      Primodil-L is a fixed dose combination of losartan (an angiotensin-II blocker) and amlodipine (a long acting calcium channel blocker) for the management of mild to moderate hypertension where the B.P is not adequately controlled by individual agents alone. Agents acting on renin angiotensin system and calcium channel blockers have an established role in the management of hypertension. Drugs of these two classes reduce B.P by complimentary mechanisms and offer distinct therapeutic advantages. These two potent antihypertensives coupled with less likelihood side effects would be able to achieve the desired goal of maintaining greater reduction in B.P.
      Indications
      Hypertension with nephropathy
      Composition
      Each tab contains:
       

      Amlodipine
      5 mg

      Losartan
      50 mg

      Dosage
      Once daily.
      Side Effects
      The adverse effects seen with the combination were mild in nature. The common side effects are oedema of feet, chest pain, body ache, giddiness and constipation which were mild in nature.
      Presentation
      PRIMODIL-L is available as a strip of 10 tablets
      Encardil 2.5
      Description
      Encardil contains Enalapril. Enalapril is an antihypertensive agent. It belongs to the second generation of Angiotensin Converting Enzyme (ACE) inhibitors. Enalapril is a prodrug. It gets hydrolysed in the liver to its active form Enalaprilat, which inhibits the Angiotensin Converting Enzyme.
      Indications
      Hypertension
      Congestive heart failure
      Post MI
      Composition
      Each uncoated tablet contains:
      Enalapril Maleate - 2.5 mg
      Dose
      Hypertension: Therapy can be initiated with 2.5 - 5 mg O.D. Maintenance dose is 5 to 20 mg O.D. In elderly patients with impaired renal function, it can be started with 2.5 mg O.D.

      Congestive heart failure: Start with 2.5 mg O.D. and can be increased to 10 to 20 mg daily. Post MI: Dose has to be titrated as per the requirement.
      Side effects
      Encardil is well tolerated. Some of the mild side effects include cough, hyperkalemia and skin rash.
      Presentation
      Encardil is available as a strip of 10 tablets.
      Encardil 5
      Description
      Encardil contains Enalapril. Enalapril is an antihypertensive agent. It belongs to the second generation of Angiotensin Converting Enzyme (ACE) inhibitors. Enalapril is a prodrug. It gets hydrolysed in the liver to its active form Enalaprilat, which inhibits the Angiotensin Converting Enzyme.
      Indications
      Hypertension
      Congestive heart failure
      Post MI
      Composition
      Each uncoated tablet contains:
      Enalapril Maleate - 5 mg
      Dose
      Hypertension: Therapy can be initiated with 2.5 - 5 mg O.D. Maintenance dose is 5 to 20 mg O.D. In elderly patients with impaired renal function, it can be started with 2.5 mg O.D.

      Congestive heart failure: Start with 2.5 mg O.D. and can be increased to 10 to 20 mg daily. Post MI: Dose has to be titrated as per the requirement.
      Side effects
      Encardil is well tolerated. Some of the mild side effects include cough, hyperkalemia and skin rash.
      Presentation
      Encardil is available as a strip of 10 tablets.
      Encardil 10
      Description
      Encardil contains Enalapril. Enalapril is an antihypertensive agent. It belongs to the second generation of Angiotensin Converting Enzyme (ACE) inhibitors. Enalapril is a prodrug. It gets hydrolysed in the liver to its active form Enalaprilat, which inhibits the Angiotensin Converting Enzyme.
      Indications
      Hypertension
      Congestive heart failure
      Post MI
      Composition
      Each uncoated tablet contains:
      Enalapril Maleate - 10 mg
      Dose
      Hypertension: Therapy can be initiated with 2.5 - 5 mg O.D. Maintenance dose is 5 to 20 mg O.D. In elderly patients with impaired renal function, it can be started with 2.5 mg O.D.

      Congestive heart failure: Start with 2.5 mg O.D. and can be increased to 10 to 20 mg daily. Post MI: Dose has to be titrated as per the requirement.
      Side effects
      Encardil is well tolerated. Some of the mild side effects include cough, hyperkalemia and skin rash.
      Presentation
      Encardil is available as a strip of 10 tablets.
      Nevol 2.5
      Description
      Nebivolol is a selective B1-receptor antagonist. Blocking the beta-receptors in the heart causes the heart to beat more slowly and with less force. This means that the pressure at which blood is pumped out of the heart to the rest of the body is reduced.

      It has mild vasodilating properties, possible due to an interaction with the L-arginine/nitric oxide pathway, which widens the blood vessels.

      Nebivolol with its distinct mechanism of action is very good antihypertensive and useful for the treatment of mild to moderate hypertension.
      Indications
      Treatment of mild to moderate essential hypertension
      Composition
      Each tablet contains:
      Nebivolol Hydrochloride   2.5 mg
      Dosage
      5 mg tablet once daily, preferable at the same time of the day, with or without meals.
      Patients with renal insufficiency the recommended starting dose is 2.5 mg daily.
      The daily dose may be increased to 5 mg if needed.
      Elderly patients over 65 years, the recommended starting dose is 2.5 mg daily. The dose may be increased to 5 mg daily if needed.
      Side Effects
      Headache, bradycardia, diarrhea, constipation, nausea, vomiting or abdominal pain.
      Contraindications
      Hypersensitivity to Nebivolol
      Liver function impairment
      Cardiogenic shock
      Not recommended for use in pregnancy, lactation and children
      Precaution
      Use cautiously in patients with history of bronchial asthma.
      Presentation
      Nevol is available as a strip of 10 tablets.
      Nevol 5
      Description
      Nebivolol is a selective B1-receptor antagonist. Blocking the beta-receptors in the heart causes the heart to beat more slowly and with less force. This means that the pressure at which blood is pumped out of the heart to the rest of the body is reduced.

      It has mild vasodilating properties, possible due to an interaction with the L-arginine/nitric oxide pathway, which widens the blood vessels.

      Nebivolol with its distinct mechanism of action is very good antihypertensive and useful for the treatment of mild to moderate hypertension.
      Indications
      Treatment of mild to moderate essential hypertension
      Composition
      Each tablet contains:
      Nebivolol Hydrochloride   5mg
      Dosage
      5 mg tablet once daily, preferable at the same time of the day, with or without meals.
      Patients with renal insufficiency the recommended starting dose is 2.5 mg daily.
      The daily dose may be increased to 5 mg if needed.
      Elderly patients over 65 years, the recommended starting dose is 2.5 mg daily. The dose may be increased to 5 mg daily if needed.
      Side Effects
      Headache, bradycardia, diarrhea, constipation, nausea, vomiting or abdominal pain.
      Contraindications
      Hypersensitivity to Nebivolol
      Liver function impairment
      Cardiogenic shock
      Not recommended for use in pregnancy, lactation and children
      Precaution
      Use cautiously in patients with history of bronchial asthma.
      Presentation
      Nevol is available as a strip of 10 tablets.
      Nevol H
      Description
      Hypertension is a multifactorial disease. One drug addresses only one physiological pathway of many that leads to hypertension.

      The other mechanisms of blood pressure regulation will be stimulated and play major role in raising the B.P. Hence two or more agents from different pharmacological classes are often needed to achieve adequate blood pressure control.

      Nebivolol has dual mode of action: It is a competitive & selective β1-receptor antagonist & it has mild vasodilating properties.

      Nebivolol reduces heart rate & blood pressure at rest & during exercise. Acute effects of thiazides are as a result of a reduction in blood volume and cardiac output, secondary to a natriuretic effect. Better blood pressure control can be achieved by using this combination.
      Indications
      Management of hypertension not responding to monotherapy.
      Hypertension with left ventricular failure.
      Composition
      Each tablet contains:
      Nebivolol Hydrochloride - 5 mg
      Hydrochlorothiazide - 12.5 mg
      Dosage
      One tablet daily preferably at the same time of the day.
      Side Effects
      Anaphylactic reaction, Headache, Dizziness, Paresthesia, Constipation, Nausea, Dyspnoea.
      Contraindications
      Cardiogenic shock, overt cardiac failure, Heart block, bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs
      Presentation
      Nevol-H is available as a strip of 10 tablets.
      Telmed 20 MG
      Description
      Telmisartan, a unique angiotensin II receptor antagonist used for the treatment of hypertension, also function as a partial agonist of PPAR gamma receptor; and reduce glucose, insulin, and triglyceride levels. None of the other available angiotensin II receptor antagonists activate PPAR when tested at concentrations typically achieved in plasma with conventional oral dosing. In contrast to ordinary antihypertensive and antidiabetic agents, molecules that can simultaneously block the angiotensin II receptor and activate PPAR have the potential to treat both hypertension and biochemical features of the metabolic syndrome and could provide unique opportunities for the prevention and treatment of diabetes and cardiovascular disease in high-risk populations.
      Indications
      TELMED is indicated for the treatment hypertension with nephropathy.
      Composition
      Each tablet contains:
       

      Telmisartan
      20 mg

      Dosage
      Usual starting dose of TELMED is 20 mg once a day;
      Side Effects
      Fatigue, sinusitis, respiratory tract infection.
      Presentation
      Telmed 20 MG is available as a strip of 10 tablets
      Telmed 40 MG
      Description
      Telmisartan, a unique angiotensin II receptor antagonist used for the treatment of hypertension, also function as a partial agonist of PPAR gamma receptor; and reduce glucose, insulin, and triglyceride levels. None of the other available angiotensin II receptor antagonists activate PPAR when tested at concentrations typically achieved in plasma with conventional oral dosing. In contrast to ordinary antihypertensive and antidiabetic agents, molecules that can simultaneously block the angiotensin II receptor and activate PPAR have the potential to treat both hypertension and biochemical features of the metabolic syndrome and could provide unique opportunities for the prevention and treatment of diabetes and cardiovascular disease in high-risk populations.
      Indications
      TELMED is indicated for the treatment hypertension with nephropathy.
      Composition
      Each tablet contains:
       

      Telmisartan
      40 mg

      Dosage
      Usual starting dose of TELMED is 40 mg once a day;
      Side Effects
      Fatigue, sinusitis, respiratory tract infection.
      Presentation
      Telmed 40 MG is available as a strip of 10 tablets
      Telmed 80 MG
      Description
      Telmisartan, a unique angiotensin II receptor antagonist used for the treatment of hypertension, also function as a partial agonist of PPAR gamma receptor; and reduce glucose, insulin, and triglyceride levels. None of the other available angiotensin II receptor antagonists activate PPAR when tested at concentrations typically achieved in plasma with conventional oral dosing. In contrast to ordinary antihypertensive and antidiabetic agents, molecules that can simultaneously block the angiotensin II receptor and activate PPAR have the potential to treat both hypertension and biochemical features of the metabolic syndrome and could provide unique opportunities for the prevention and treatment of diabetes and cardiovascular disease in high-risk populations.
      Indications
      TELMED is indicated for the treatment hypertension with nephropathy.
      Composition
      Each tablet contains:
       

      Telmisartan
      80 mg

      Dosage
      One tablet once daily
      Side Effects
      Fatigue, sinusitis, respiratory tract infection.
      Presentation
      Telmed 80 MG is available as a strip of 10 tablets
      TELMED – AH 40
      Description
      Hypertension being a multifactorial disease, management of hypertension often requires multiple drugs. 23%–52% patients require three or more antihypertensive agents for BP control and to achieve JNC VII target. Combining drugs with complimentary modes of action is practically correct, as it is more likely to achieve better BP control. Combining drugs reduces the adverse events of the high dose monotherapies. A triple drug combination therapy would be a desirable treatment option for hypertension uncontrolled on dual drug. Combining different drugs in a single pill leads to better compliance and hence better BP control.
      Indications
      Hypertension uncontrolled on dual therapy
      Stage 2 hypertension
      Composition
      Telmed - AH 40
       

      Each tablet contains:
       

      Telmisartan
      40 mg

      Amlodipine
      5 mg

      Hydrochlorothiazide
      12.5mg

      Dosage
      1 tablet to be taken once daily preferably at the same time everyday
      Presentation
      Telmed - AH 40 is available as a strip of 10 tablets
      TELMED – AH 80
      Description
      Hypertension being a multifactorial disease, management of hypertension often requires multiple drugs. 23%–52% patients require three or more antihypertensive agents for BP control and to achieve JNC VII target. Combining drugs with complimentary modes of action is practically correct, as it is more likely to achieve better BP control. Combining drugs reduces the adverse events of the high dose monotherapies. A triple drug combination therapy would be a desirable treatment option for hypertension uncontrolled on dual drug. Combining different drugs in a single pill leads to better compliance and hence better BP control.
      Indications
      Hypertension uncontrolled on dual therapy
      Stage 2 hypertension
      Composition
      Telmed - AH 80
       

      Each tablet contains:
       

      Telmisartan
      80 mg

      Amlodipine
      5 mg

      Hydrochlorothiazide
      12.5mg

      Dosage
      1 tablet to be taken once daily preferably at the same time everyday
      Presentation
      Telmed - AH 80 is available as a strip of 10 tablets
      TELMED –AM
      Description
      The goal set by JNC VII in diabetic hypertensive is 130/80 mm Hg that is very difficult to achieve with monotherapy. However, older antihypertensive agents such as thiazide diuretics and beta-blockers have potentially adverse effects on glucose and lipid metabolism and may even exacerbate the metabolic syndrome and increase risk of type II diabetes. Thus, there is a need for an antihypertensive drug combination that can achieve the JNC VII recommended goal without compromising the lipid profile and glycaemic control. Telmisartan plus Amlodipine are two potent antihypertensives with less side effects that would be able to achieve the desired goal of maintaining greater reduction in B.P.
      Indications
      Diabetic hypertensives
      Hypertension not controlled with monotherapy
      Composition
      Each tablet contains:
       

      Telmisartan
      40 mg

      Amlodipine
      5 mg

      Dosage
      One tablet once daily
      Side Effects
      URTI, Dizziness, Diarrhea, ankle edema, Headache
      Presentation
      Telmed-AM is available as a strip of 10 tablets.
      TELMED –H 40
      Description
      Diuretics are effective antihypertensive drugs. In long-term trials, diuretics have been shown to reduce the incidence of stroke, congestive heart failure, coronary artery disease and total mortality from cardiovascular disease. Telmisartan exerts antihypertensive effect by selectively blocking the angiotensin II type 1 (AT1) receptors. Hypokalemia caused by diuretics, counteract the positive cardiovascular benefits of blood pressure reduction. Telmisartan protects against potassium depletion, a common side effect of thiazide monotherapy. Thus low dose hydrochlorothiazide in combination with Telmisartan does not counteract the positive cardiovascular benefits of blood pressure reduction and helps in achieving the desired goal of BP.
      Indications
      Hypertension uncontrolled with monotherapy
      Composition
      Each tablet contains :
       

      Telmisartan
      40 mg

      Hydrochlorothiazide
      12.5 mg

      Dosage
      One tablet daily
      Side Effects
      Most adverse experiences are mild in intensity and transient in nature like Fatigue, dizziness, nausea, sinusitis, respiratory tract infections.
      Presentation
      TELMED –H 40 is available as a strip of 10 tablets
      TELMED –H 80
      Description
      Diuretics are effective antihypertensive drugs. In long-term trials, diuretics have been shown to reduce the incidence of stroke, congestive heart failure, coronary artery disease and total mortality from cardiovascular disease. Telmisartan exerts antihypertensive effect by selectively blocking the angiotensin II type 1 (AT1) receptors. Hypokalemia caused by diuretics, counteract the positive cardiovascular benefits of blood pressure reduction. Telmisartan protects against potassium depletion, a common side effect of thiazide monotherapy. Thus low dose hydrochlorothiazide in combination with Telmisartan does not counteract the positive cardiovascular benefits of blood pressure reduction and helps in achieving the desired goal of BP.
      Indications
      Hypertension uncontrolled with monotherapy
      Composition
      Each tablet contains :
       

      Telmisartan
      80 mg


      Hydrochlorothiazide
      12.5 mg

      Dosage
      One tablet daily
      Side Effects
      Most adverse experiences are mild in intensity and transient in nature like Fatigue, dizziness, nausea, sinusitis, respiratory tract infections.
      Presentation
      TELMED –H 80 is available as a strip of 10 tablets
      TELMED BETA 25
      Description
      Fixed-dose combination that target complementary BP-lowering mechanisms like Heart rate, Peripheral Resistance and Cardiac Output provides an effective approach for better BP control. Telmisartan exerts antihypertensive effect by selectively blocking AT1 receptors; resulting into blocking the actions of angiotensin II, including vasoconstriction, sodium and water retention and sympathetic nervous system activation. Metoprolol is cardio selective β1 blocker. It causes decrease in heart rate and cardiac output and thus decreases blood pressure.
      Indications
      Hypertension uncontrolled on monotherapy
      Hypertension with heart failure
      Hypertension with CAD
      Composition
      Each Tablet of Telmed Beta Consists of:
       

      Metoprolol
      25 mg

      Telmisartan
      40 mg

      Presentation
      TELMED BETA 25 is available as a strip of 10 tablets
      TELMED BETA 50
      Description
      Fixed-dose combination that target complementary BP-lowering mechanisms like Heart rate, Peripheral Resistance and Cardiac Output provides an effective approach for better BP control. Telmisartan exerts antihypertensive effect by selectively blocking AT1 receptors; resulting into blocking the actions of angiotensin II, including vasoconstriction, sodium and water retention and sympathetic nervous system activation. Metoprolol is cardio selective β1 blocker. It causes decrease in heart rate and cardiac output and thus decreases blood pressure.
      Indications
      Hypertension uncontrolled on monotherapy
      Hypertension with heart failure
      Hypertension with CAD
      Composition
      Each Tablet of Telmed Beta Consists of:
       

      Metoprolol
      50 mg

      Telmisartan
      40 mg

      Presentation
      TELMED BETA 50 is available as a strip of 10 tablets
      Telmed CT 40 tablet
      Composition
      Each tablet contains:
      Telmisartan 40 mg
      Chlorthalidone 12.5 mg
      Indications
      Hypertension & CV risk
      Presentation
      TELMED CT 40 is available as a strip of 10 tablets
      Telmed CT 80 tablet
      Composition
      Each tablet contains:
      Telmisartan 80 mg
      Chlorthalidone 12.5 mg
      Indications
      Hypertension & CV risk
      Presentation
      TELMED CT 80 is available as a strip of 10 tablets
      Telmed ACT 40 tablet
      Composition
      Each tablet contains:
      Telmisartan 40 mg
      Amlodipine 5 mg
      Chlorthalidone 12.5 mg
      Indications
      Hypertension uncontrolled on dual therapy
      Stage II hypertension with nephropathy
      Hypertension with CKD
      Presentation
      Telmed-ACT 40 is available as a strip of 10 tablets
      Telmed ACT 80 tablet
      Composition
      Each tablet contains:
      Telmisartan 80 mg
      Amlodipine 5 mg
      Chlorthalidone 12.5 mg
      Indications
      Hypertension uncontrolled on dual therapy
      Stage II hypertension with nephropathy
      Hypertension with CKD
      Presentation
      Telmed-ACT 80 is available as a strip of 10 tablets
      CILDIP 5
      Description
      Cilnidipine is a Calcium channel blocker. It block both type of calcium channel. Inhibits L-type calcium channel resulting in vasodilation .Inhibits N-type calcium channel resulting in no sympathetic activation thus reduces heart rate. Both these effects leads to decrease in blood pressure with less chances of ankle/pedal edema. Cilnidipine also Improves insulin sensitivity & Increases Nitric Oxide production thus improves endothelial function.
      Indications
      In the management of :
      Hypertension
      Hypertension with diabetes mellitus
      Hypertension and chronic renal insufficiency
      Hypertension in elderly
      Composition
      Each tablet contains :
       

      Cilnidipine
      5 mg

      Dosage & Administration
      Cilnidipine's starting dose is 5 mg/day orally.
      Maximum 20mg/day.
      Presentation
      Cildip is available as a strip of 10 tablets
      CILDIP 10
      Description
      Cilnidipine is a Calcium channel blocker. It block both type of calcium channel. Inhibits L-type calcium channel resulting in vasodilation .Inhibits N-type calcium channel resulting in no sympathetic activation thus reduces heart rate. Both these effects leads to decrease in blood pressure with less chances of ankle/pedal edema. Cilnidipine also Improves insulin sensitivity & Increases Nitric Oxide production thus improves endothelial function.
      Indications
      In the management of :
      Hypertension
      Hypertension with diabetes mellitus
      Hypertension and chronic renal insufficiency
      Hypertension in elderly
      Composition
      Each tablet contains :
       

      Cilnidipine
      10 mg

      Dosage & Administration
      Cilnidipine's starting dose is 5 mg/day orally.
      Maximum 20mg/day.
      Presentation
      Cildip is available as a strip of 10 tablets
      CILDIP 20
      Description
      Cilnidipine is a Calcium channel blocker. It block both type of calcium channel. Inhibits L-type calcium channel resulting in vasodilation .Inhibits N-type calcium channel resulting in no sympathetic activation thus reduces heart rate. Both these effects leads to decrease in blood pressure with less chances of ankle/pedal edema. Cilnidipine also Improves insulin sensitivity & Increases Nitric Oxide production thus improves endothelial function.
      Indications
      In the management of :
      Hypertension
      Hypertension with diabetes mellitus
      Hypertension and chronic renal insufficiency
      Hypertension in elderly
      Composition
      Each tablet contains :
       

      Cilnidipine
      20 mg

      Dosage & Administration
      Cilnidipine's starting dose is 5 mg/day orally.
      Maximum 20mg/day.
      Presentation
      Cildip is available as a strip of 10 tablets
      CILDIP T
      Description
      Telmisartan amongst ARBs, acts as a partial agonist of PPAR- γ (Peroxisome Proliferator Activated Receptor- Gamma) receptor, helps in improving blood glucose and lipid profile. Cilnidipine improve GLUT-4 receptor, which lead to increase in glucose uptake. Thus, improve insulin sensitivity. Thus, combination of Telmisartan with Cilnidipine improves glucose levels and insulin sensitivity along with decrease in blood pressure. In Renally compromised patients Telmisartan which is mainly excreted through hepatic route can be safely given to hypertensive patients who suffer from nephropathy and there is no need to reduce the dose. N-type Ca2+ channels are present in both afferent and efferent arterioles. Their inhibition by Cilnidipine elicits vasodilation of both arterioles, leading to the reduction in glomerular pressure. This results in decrease in proteinuria. Thus, combination of telmisartan and Cilnidipine is beneficial in the hypertensives with kidney disease.
      Indications
      Stage II hypertension
      Hypertension uncontrolled with monotherapy
      Diabetic hypertensive patients
      Hypertension with nephropathy
      Composition
      Each tablet contains :
       

      Telmisartan
      40 mg

      Cilnidipine
      10 mg

      Dosage
      Once daily preferably at the same time of the day
      Presentation
      Cildip is available as a strip of 10 tablets
      Cildip 3D tablet
      Composition
      Each tablet contains:
      Cilnidipine 10 mg
      Telmisartan 40 mg
      Chlorthalidone 6.25 mg
      Indications
      Stage II & Refractory Hypertension
      Presentation
      Cildip 3D is available as a strip of 10 tablets