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Suprakare
Suprakare is the 2nd biggest divison of Medley catering mainly to Orthopaedic & Gastroenterology segments. It is also the fastest growing division of Medley & has one of the most innovative and first time launches in the Indian Pharmaceutical Market like DOMPAN (Domperidone plus pantoprazole), Ostium k2 ( 1st brand of Vitamin K27 combination in india), Tazocef (Tazobactam plus Ceftriaxone), Acenac-N (Aceclofenac plus Pregabalin) to name a few. Today, all of them feature amongst the top 5 brands in their respective segments.

Analgesic and Anti-inflammatory

Acenac-N
Description
Mixed pain syndrome is associated with conditions like low back pain, sciatica, radiculopathy (cervical & lumbar) & chronic post operative pain. Aceclofenac takes care of nociceptive (inflammatory) pain by inhibiting prostaglandin synthesis. Pregabalin binds to α2-δ subunit of voltage gated calcium channels & reduces the release of neurotransmitters like glutamate and substance P. This reduction in neurotransmitter release accounts for pregabalin's analgesic action. Both component of mixed pain syndrome nociceptive (inflammatory) & neuropathic pain are taken care by aceclofenac & pregabalin respectively.
Indications
Low back pain
Sciatica
Cervical radiculopathy
Lumbar radiculopathy
Post-operative pain following orthopedic surgery
Composition
Each tablet contains :
Aceclofenac Sustained release - 200 mg
Pregabalin Sustained release - 75 mg
Dose
1 tablet once daily or as directed by the physician.
Adverse effects
Dizziness, somnolence, dry mouth, edema, weight gain, abdominal pain.
Contraindications
Hypersensitivity to any of the ingredients.
Presentation
Acenac- N is available as a strip of 10 tablets.