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Nutrakare

Antibiotics

Kefodime 50 Dt
Description
Cefpodoxime is an extended spectrum semi-synthetic antibiotic which belongs to the third generation of cephalosporins. It inhibits bacterial cell wall synthesis leading to bacterial cell death. Cefpodoxime is given as Cefpodoxime proxetil (prodrug) which is hydrolyzed in the intestinal epithelium to release active drug Cefpodoxime. It is active against broad spectrum of Gram +ve & Gram -ve bacteria. Organisms resistant to penicillins and some cephalosporins due to their b-lactamases secretion are susceptible to Cefpodoxime. It is effective for longer duration with higher clinical success rate and low incidence of side effects.
Indications
Lower respiratory tract infections
Upper respiratory tract infections
Urinary tract infections including gonorrhea, cystitis
Skin and soft tissue infections
Gynecological infections
Acute otitis media
Composition
Each Dispersible tablet contains:
 

Cefpodoxime Proxetil
50 mg
Dosage
Adults : 200mg BID or 400mg OD for 7 -10 days.

In case of URTI & Uncomplicated UTI, dose can be reduced to 100mg BID or 200mg OD. Only single dose of 200mg is recommended in case of Uncomplicated Gonorrhea.
Children : 10 mg/kg/ days or 5 mg/kg every 12 hrs for 10 day (max 400 mg/ day).

Precautions
Pregnancy
Not enough studies to document use in pregnancy.

Nursing Mothers
Cefpodoxime is secreted in human milk. Use with caution.

Pediatric Use
Safety and effectiveness not established in infants.

 
(less than two months old)
Adverse reactions
Diarrhea, Nausea, Vomiting, Abdominal pain, vaginal fungal infections & pruritus.
Contraindications
Known hypersensitivity to cefpodoxime proxetil.
Presentation
Kefodime 50 is available as a strip of 10 tablets.
Kefodime 100 Dt
Description
Cefpodoxime is an extended spectrum semi-synthetic antibiotic which belongs to the third generation of cephalosporins. It inhibits bacterial cell wall synthesis leading to bacterial cell death. Cefpodoxime is given as Cefpodoxime proxetil (prodrug) which is hydrolyzed in the intestinal epithelium to release active drug Cefpodoxime. It is active against broad spectrum of Gram +ve & Gram -ve bacteria. Organisms resistant to penicillins and some cephalosporins due to their b-lactamases secretion are susceptible to Cefpodoxime. It is effective for longer duration with higher clinical success rate and low incidence of side effects.
Indications
Lower respiratory tract infections
Upper respiratory tract infections
Urinary tract infections including gonorrhea, cystitis
Skin and soft tissue infections
Gynecological infections
Acute otitis media
Composition
Each Dispersible tablet contains:
 

Cefpodoxime Proxetil
100 mg
Dosage
Adults : 200mg BID or 400mg OD for 7 -10 days.

In case of URTI & Uncomplicated UTI, dose can be reduced to 100mg BID or 200mg OD. Only single dose of 200mg is recommended in case of Uncomplicated Gonorrhea.
Children : 10 mg/kg/ days or 5 mg/kg every 12 hrs for 10 day (max 400 mg/ day).

Precautions
Pregnancy
Not enough studies to document use in pregnancy.

Nursing Mothers
Cefpodoxime is secreted in human milk. Use with caution.

Pediatric Use
Safety and effectiveness not established in infants.

 
(less than two months old)
Adverse reactions
Diarrhea, Nausea, Vomiting, Abdominal pain, vaginal fungal infections & pruritus.
Contraindications
Known hypersensitivity to cefpodoxime proxetil.
Presentation
Kefodime 100 is available as a strip of 10 tablets.
Kefodime 200 Dt
Description
Cefpodoxime is an extended spectrum semi-synthetic antibiotic which belongs to the third generation of cephalosporins. It inhibits bacterial cell wall synthesis leading to bacterial cell death. Cefpodoxime is given as Cefpodoxime proxetil (prodrug) which is hydrolyzed in the intestinal epithelium to release active drug Cefpodoxime. It is active against broad spectrum of Gram +ve & Gram -ve bacteria. Organisms resistant to penicillins and some cephalosporins due to their b-lactamases secretion are susceptible to Cefpodoxime. It is effective for longer duration with higher clinical success rate and low incidence of side effects.
Indications
Lower respiratory tract infections
Upper respiratory tract infections
Urinary tract infections including gonorrhea, cystitis
Skin and soft tissue infections
Gynecological infections
Acute otitis media
Composition
Each film coated tablet contains:
 

Cefpodoxime Proxetil
200 mg
Dosage
Adults : 200mg BID or 400mg OD for 7 -10 days.

In case of URTI & Uncomplicated UTI, dose can be reduced to 100mg BID or 200mg OD. Only single dose of 200mg is recommended in case of Uncomplicated Gonorrhea.
Children : 10 mg/kg/ days or 5 mg/kg every 12 hrs for 10 day (max 400 mg/ day).

Precautions
Pregnancy
Not enough studies to document use in pregnancy.

Nursing Mothers
Cefpodoxime is secreted in human milk. Use with caution.

Pediatric Use
Safety and effectiveness not established in infants.

 
(less than two months old)
Adverse reactions
Diarrhea, Nausea, Vomiting, Abdominal pain, vaginal fungal infections & pruritus.
Contraindications
Known hypersensitivity to cefpodoxime proxetil.
Presentation
Kefodime 200 is available as a strip of 10 tablets.
Kefodime Dry Syrup
Description
Cefpodoxime is an extended spectrum semi-synthetic antibiotic which belongs to the third generation of cephalosporins. It inhibits bacterial cell wall synthesis leading to bacterial cell death. Cefpodoxime is given as Cefpodoxime proxetil (prodrug) which is hydrolyzed in the intestinal epithelium to release active drug Cefpodoxime. It is active against broad spectrum of Gram +ve & Gram -ve bacteria. Organisms resistant to penicillins and some cephalosporins due to their b-lactamases secretion are susceptible to Cefpodoxime. It is effective for longer duration with higher clinical success rate and low incidence of side effects.
Indications
Lower respiratory tract infections
Upper respiratory tract infections
Urinary tract infections including gonorrhea, cystitis
Skin and soft tissue infections
Gynecological infections
Acute otitis media
Composition
Each 5 ml of reconstituted syrup contains:
 

Cefpodoxime Proxetil
50 mg
Dosage
Adults : 200mg BID or 400mg OD for 7 -10 days.

In case of URTI & Uncomplicated UTI, dose can be reduced to 100mg BID or 200mg OD. Only single dose of 200mg is recommended in case of Uncomplicated Gonorrhea.
Children : 10 mg/kg/ days or 5 mg/kg every 12 hrs for 10 day (max 400 mg/ day).

Precautions
Pregnancy
Not enough studies to document use in pregnancy.

Nursing Mothers
Cefpodoxime is secreted in human milk. Use with caution.

Pediatric Use
Safety and effectiveness not established in infants.

 
(less than two months old)
Adverse reactions
Diarrhea, Nausea, Vomiting, Abdominal pain, vaginal fungal infections & pruritus.
Contraindications
Known hypersensitivity to cefpodoxime proxetil.
Presentation
Kefodime dry syrup is available as a bottle of 30 ml.
CO2 Tab
Description
It is a combination of Cefixime (3rd generation cephalosporin) & Ofloxacin (fluoroquinolone) for the treatment of Typhoid fever, Urinary tract infection, & Respiratory tract infection. Cefixime kills bacteria by inhibiting bacterial cell wall synthesis & ofloxacin kills by affecting bacterial DNA gyrase. As both acts on different target sites provide synergistic effect against most of pathogens, also both Cefixime & Ofloxacin have been recommended by the WHO for the treatment of Typhoid.
Indications
Typhoid fever
Pyrexia of unknown origin
Urinary tract infection
Community acquired pneumoniae
Composition
Each tablet consist of:
 

Ofloxacin
200 mg

Cefixime
200 mg
Side Effects
nausea & vomiting, abdominal discomfort, headache, dizziness may occur.

Contraindications
Cephalosporin hypersensitivity.
Presentation
CO2 is available as a strip of 10 tablets.
CO2H Tab
Description
It is a combination of Cefixime (3rd generation cephalosporin) & Ofloxacin (fluoroquinolone) for the treatment of Typhoid fever, Urinary tract infection, & Respiratory tract infection. Cefixime kills bacteria by inhibiting bacterial cell wall synthesis & ofloxacin kills by affecting bacterial DNA gyrase. As both acts on different target sites provide synergistic effect against most of pathogens, also both Cefixime & Ofloxacin have been recommended by the WHO for the treatment of Typhoid.
Indications
Typhoid fever
Pyrexia of unknown origin
Urinary tract infection
Community acquired pneumoniae
Composition
Each tablet consist of:
 

Ofloxacin
100 mg

Cefixime
100 mg
Side Effects
nausea & vomiting, abdominal discomfort, headache, dizziness may occur.

Contraindications
Cephalosporin hypersensitivity.
Presentation
CO2H is available as a strip of 10 tablets.
CO2 Dry Syrup
Description
It is a combination of Cefixime (3rd generation cephalosporin) & Ofloxacin (fluoroquinolone) for the treatment of Typhoid fever, Urinary tract infection, & Respiratory tract infection. Cefixime kills bacteria by inhibiting bacterial cell wall synthesis & ofloxacin kills by affecting bacterial DNA gyrase. As both acts on different target sites provide synergistic effect against most of pathogens, moreover both Cefixime & Ofloxacin have been recommended by the WHO for the treatment of Typhoid.
Indications
Typhoid fever
Pyrexia of unknown origin
Urinary tract infection
Community acquired pneumoniae
Composition
Each 5ml consist of:
 

Ofloxacin
50 mg

Cefixime
50 mg
Dosage
5ml twice a day.

Side Effects
Nausea & vomiting, abdominal discomfort, headache, dizziness may occur.

Contraindications
Cephalosporin hypersensitivity.
Presentation
CO2 dry syrup is available as a bottle of 30 ml.