Dyspepsia is predominantly result of the problem with gastrointestinal motility. However most of the symptoms of dyspepsia are due to injurious effects of acid peptic refluxate on the oesophageal epithelium. Hence the combination of drugs one of which suppressing acid and the other improving gastrointestinal motility is effective in treating reflux disease. Pantoprazole, a proton pump inhibitor. Domperidone, a prokinetic agent is an effective and safe agent to improve gastrointestinal motility.
Domperidone increases LES pressure and enhances the upper gastrointestinal motility and thus treats the underlying pathophysiological causes of dyspepsia & GERD.
Thus this combination of pantoprazole and domperidone effectively treats the symptoms and the underlying causes of reflux diseases.
Drug induced gastritis
Each enteric coated tablet contains
Domperidone - 10 mg
Pantoprazole - 20 mg
Dompan - One tablet twice daily.
Minor side effects like headache may occur.
No special precautions are required.
Dompan are available as a strip of 10 tablets.